Statement of the problem

The company portfolio has multiple R&D programs in various stages of development.  Each program also
might have several potential business development strategies (e.g. in-house development vs. in-licensing,
aggressive vs. conservative strategy). Company has limited resources – budget, FTEs, manufacturing
capacity. Company has operational and strategic goals (e.g. revenue target, growth rate), as well as
business rules such as financial ratios (e.g. cost/revenue), various benchmarking rules, management
preferences and others, defining unique company environment.

Challenge

  • Selecting maximum value portfolio
  • Allocating limited resources across multiple development programs to align with
    enterprise long-term strategy and operational goals
  • Creating a balance between long-term and short-term goals
  • Defining right investment level for each program

Solution

ORBee Consulting offers a framework for optimal drug development portfolio planning.
This optimization approach enhances many currently used techniques by incorporating
multiple resource limitations, strategic and operational corporate goals and business rules.

Proposed framework will derive the following:

  • An optimal set of funded programs including partnerships.
  • Optimal budget and revenue allocation across therapeutic areas and development
    stages
  • Multiple “what if” scenarios (resource reallocation due to a significant event, program
    priority status, etc.)
  • Other customized metrics
Drug Development Portfolio Optimization